21GRAMS

The creative agency of Real Chemistry

Medicine can’t move people like sneakers do. Real Chemistry Can.

21GRAMS isn’t just a name. It’s the philosophy and intention behind everything we do. Legend says it’s the weight of the soul, a fitting name for an agency built to tap into the human spirit. Understanding audiences and what matters to them isn’t just our specialty. It’s what healthcare was missing.

Our mission is to make medicine feel more inspiring than sneakers. Because medicine changes people’s lives. Sneakers just go on feet. Since day one, 21GRAMS has proven that the bar for creativity shouldn’t be lower because this is about health. It should be higher because there’s more at stake. And that’s how we’ve become globally recognized for highly effective healthcare advertising that actually “gets” people.

1st

Ever Gold Lion awarded at Cannes for branded, regulated, pharmaceutical work.

What we do
How we get it done

What we do

At 21GRAMS, we specialize in strategic and insight-driven creative work that moves people. From early stages through launch and beyond, we deliver incredibly effective work that helps our clients outperform projections, and makes audiences feel.

We can (and have) done it all, for brands big and small, end-to-end. The biggest difference: we are 100% connected with Real Chemistry. We operate as one company and can assemble an integrated team overnight. If you’re looking for a brand-building, market-shaping, full-service creative AOR, and so much more, look no further. Contact us.

How we get it done

ROOM42 is our full-scale global production hub and your dedicated production engine, fully integrated to bring ideas to life.

This room has done it all, from intimate documentary films to video, digital, print, audio, animation, podcasts, video games, digital experiences and more, all with robust QC processes.

Why it matters? As the backbone of our execution model, ROOM42 ensures consistency at scale, across regions and timelines and at every stage of a brand’s lifecycle.

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Key Areas of Expertise, Just to Name a Few

Brand Building & Market Shaping

Everything you need to build your brand from belief and behavior shift alignment to journey mapping, competitive trend analysis, audience segmentation, positioning development, strategic launch planning and more.

HCP & Patient Engagement

We get to know your audiences better than they know themselves, from building narratives to campaign development, ecosystem orchestration, peer-to-peer programming, tactical planning, KOL engagement, patient community engagement and storytelling that gets results.

Production

ROOM42 is our best-in-class, full-service production company built to deliver high quality, efficient solutions for brands, from print to motion, audio, static, specialty digital and much more.

Experience

Human-centered design for patients and providers is just the beginning. We also offer design systems built for scalability, clinical-grade UX, architecture, content strategy, regulatory alignment, interactive design, empathetic design, data-driven decision-making and seamless experiences for every audience.

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Ready to make medicine feel as inspiring as sneakers?

Featured Case Studies

We create the kind of work that makes you feel. Here are 3 recent examples that raised the bar in health.

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View All

Friedreich’s Back

A dark comedy series that shed light on a rare disease

The result: 10M views and 5,000 website conversions for a community of 15,000

Read case study
Forbidden Fantasies

Identifying an unaddressed need for brands to connect with women on a more personal level

The result: +225% positive brand sentiment across all social media

Read case study
Knowbesity

A campaign that speaks directly to how people with obesity really feel

The result: a response rate 2700% above average

Read case study