Medicine can’t move people like sneakers do. Real Chemistry Can.

Medicine changes people’s lives. Sneakers just go on feet. So why do people feel more for consumer brands than the ones that can actually make them better? As the advertising agency of Real Chemistry, 21GRAMS is determined to change that. We hold health to the same standards as brands we love—and it shows. Our teams specialize in strategic and creative work that moves people by tapping into the human spirit, the 21 grams that makes people tick.

The goal? To make advertising less of an interruption and more worth your audience’s time and attention. Because it actually *gets* them. That’s how we deliver incredibly effective work that helps our clients outperform projections. And it’s what made us the most awarded healthcare network, per Cannes. But most importantly, it’s how we’ve proven—with real, regulated work—that the bar isn’t lower because this is health. The bar is higher because there is more at stake.

~0%

of the work awarded at Cannes in pharma this year came from 21GRAMS

projects produced annually across brands that consistently outperform industry benchmarks

the approximate weight in grams of all 500+ of our souls combined

But don’t take our word for it. Take theirs.

Real Chemistry feels like an extension of our team. They bring smart, strategic thinking and bold creative that consistently elevates our work. They understand the nuances of healthcare and always show up with fresh ideas and energy.

Rusty Nolen

Senior Vice President, Commercial Strategy, Kowa Pharmaceuticals
What I love most about 21GRAMS is how this environment makes creatives feel. Here, creatives have the freedom to safely explore and develop their creative identities.

Eli Joseph

Copy Supervisor
Working with patient advocates was critical to achieving the authenticity and effectiveness of our campaign. 21GRAMS played a large part in making that possible. We have a great responsibility to the rare disease community to ensure that we represent their conditions appropriately. Building that relationship with the community with this team was critical to our success.

Sundip Raval

Vice President, Head of Marketing, Rare Diseases, Biogen

We can answer any need you may have, any time. (And plenty more, just in case.)

Video & Audio Production

Print Production

Brand Building and Market Shaping

Positioning Development

Experience Design

Creative Development

Strategic/Launch Planning

Patient Community Engagement

HCP & Patient Narrative & Campaign Development

Dinners with 21GRAMS

We create the kind of work that makes you feel.

Want to feel amused?

Knowing that the Friedreich ataxia (FA) community leans on humor, laughter, and social media to cope with their progressive disease, we created a dark comedy series featuring the disease’s long dead discoverer, Friedreich, to numorously educate FA patients about SKYCLARYS, resulting in 10 million views and 5,000 website conversions for a community of 15,000.

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In a market saturated with standard birth control advertising, we identified a significant cultural disconnect: women actively consume fantasy novels centered on their desires and experiences. This signaled a powerful, yet unaddressed, need for a brand to connect with women on a deeper, more personal level. So, we created Forbidden Fantasies: the first birth control campaign to celebrate women’s desires.

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In late 2023, most people were ‘over’ COVID-19, including doctors, who were somewhat immune to messaging around it. But 1.2 million vulnerable people were still shielding from COVID-19, among them transplant patients, cancer patients and the immunocompromised. Enter a hard hitting reminder of that COVID-19 is still a rolling threat.

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Obesity is a global health issue, and obesity treatments have a love/hate relationship with the media, so we created a campaign to speaks directly to how people with obesity really feel, resulting in a response rate that was 2700% above average.

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